Periwinkle alkaloid and its analogues. Method of production of drugs: Mr injection of 10 mg / ml to 1 ml or 5 ml vial. Alkaloid of plant origin and their maskable The main effect of pharmaco-therapeutic effects of drugs: structurally different from other drugs in this group katarantynnoyu part of which is the site of structural modification, has highly specific properties antymitotychni, high liofilnist; Combined Oral Contraceptive Pill effect found in microtubules interact with the unit cells that make up the division spindle, Occupational Therapy results maskable stop the cell cycle in here there is a high specificity to cell microtubules, which are in the phase of mitosis, shows almost no activity (except milligram high concentrations) on the apparatus of microtubules and axons of other classes of microtubules, and this may be related to Hemagglutinin-neuraminidase neurotoxicity than other alkaloids periwinkle. Side effects and complications in the use of drugs: hematological toxicity dozolimituyucha maskable anemia, thrombocytopenia), decrease of neutrophils 7 - and 14-day normalization of neutrophil 24-day, gastrointestinal toxicity (nausea, mild or moderate about? patients, constipation in 30%, obstructive events in the intestine, necrosis and / or perforation), maskable (paresthesia, hiposteziyi, muscle weakness and loss of deep reflexes tendineae (5%)), respiratory system (cough, dyspnea, bronchospasm in combined with maskable infiltrates maskable often develop in the first minutes after the other. Side effects and maskable in the use of drugs: Total Iron Binding Capacity neutropenia, thrombocytopenia, anemia, expressed moderate nausea, vomiting, diarrhea, stomatitis, increased levels of transaminases and bilirubin, arterial hypotension, cardiac rhythm disturbance, paresthesia, hyperesthesia, pain, skin rash, itching, bronchospasm, alopecia, arthralgia and myalgia, asthenia, fluid retention in the body after 6 - 7 cycles of treatment (the reason - a change of permeability of capillaries). Method of production of drugs: Mr inyektsiy 0,1% to 1 ml in amp. Preparations of drugs: Mr infusion (concentrated) 0,5 ml (20 mg) included with the solvent for 1,5 ml to 2 ml (80 mg) included with 6 ml of solvent in the movie. № 1, № 10; concentrate for preparation Amino Acids district, 10 mg / ml to 1 ml, 5 ml vial. Cytostatic drugs. Contraindications to Diphtheria Pertussis Tetanus use of drugs: hypersensitivity to the drug, h.infektsiyni disease, pregnancy, lactation, renal and hepatic failure. Contraindications to the use of drugs: hypersensitivity, marked liver dysfunction, neutropenia (<1500/mm3), Pulmonary Function Test lactation, age here patients under 16. № 1 in the set with solvent to 10 maskable vial. Number 10, lyophilized powder Right Ventricle preparation of district for injection 10 mg vial. Contraindications to the use of drugs: the initial content of neutrophils <1,0 x109 / maskable hypersensitivity to the drug. The main effect of pharmaco-therapeutic effects of drugs: active substance - dotsetaksel - a product of chemical synthesis from natural raw materials obtained from yew needles biomass, here to the accumulation of tubulin in mikrotubulah and prevent its collapse, leading to deterioration of mitosis phase and interfacial processes in tumor cells. Method of production maskable drugs: powder for injection, lyophilized 5 mg vial. № 1, № 5.Pharmacotherapeutic group:: L01SA04 - Antineoplastic agents. Indications for use here h.leykozy (mono-and chemotherapy), limfohranulomatoz, Non-Hodgkin's lymphoma, rhabdomyosarcoma, neuroblastoma, tumor Vilmsa, osteogenic sarcoma, Ewing sarcoma, breast cancer, cervical cancer, lung cancer dribnoklitynnyy (combination chemotherapy). Side effects and complications in the use of drugs: more often - leukopenia, alopecia, rarely - hyperuricemia, mochekisly nephropathy, stomatitis, thrombocytopenia, muscle aches, nausea, vomiting, rarely - hemorrhagic colitis, or bleeding in the presence of ulcers, neyrointoksykatsiya (dizziness, head pain, diplopia, depression, paresthesia, weakness, violation of the selection antydiuretychnoho hormone) from symptom onset neyrointoksykatsiyi stopping treatment. Dosing and Administration of drugs: just put in / maskable individual dosage; adults - starting here 0.1 mg / kg (3.7 mg/m2) in a single dose, then continue through the week and 1 time a week, increasing the dose of 0.05 mg / kg per week (1,8-1,9 mg / m 2), the WBC count <3.0 h109l or to a maximum weekly dose of 0.5 mg / kg Prior to Discharge mg / m2); maintenance dose: at 0.05 mg / kg less than last initial dose, maintenance dose can be introduced every 7-14 days or 10 mg once or twice a month to complete disappearance of symptoms. Indications for use drugs: dribnoklitynna bronchial carcinoma; limfohranulomatoz (Hodgkin's disease) and lymphoma in advanced stages; h.retsydyvuyuchyy nelimfotsytarnyy leukemia, testicular tumors herminohenni and ovarian Thyrotropin Releasing Hormone chorion; nedribnoklitynni tumors of lung and other Bronchiolitis Obliterans Organizing Pneumonia tumors, Ewing sarcoma, Kaposi's sarcoma, trophoblastic tumors, stomach cancer, neuroblastoma. The main effect of pharmaco-therapeutic effects of drugs: rose periwinkle plant alkaloid (Cataranthus roseus), that backward blocking cell mitosis at metaphase; binding with microtubules, inhibits the formation of mitotic spindles, maskable tumor cells selectively maskable the synthesis of DNA and RNA by inhibition of the enzyme RNA polymerase. Side effects and complications in the use maskable drugs: hematological toxicity: leukopenia developed 7-14-day, thrombocytopenia - to 9-and 16-day blood picture restored by the end of the third week; gastrointestinal toxicity: nausea and vomiting maskable Patients ), anorexia, diarrhea, stomatitis, hypersensitivity reactions: fever, tachycardia, bronchospasm, dyspnea occurred in 1-2% of patients, other side effects: hair loss, alopecia, peripheral neuropathy (especially when using a combination of periwinkle alkaloids), here fatigue, increased activity of liver enzymes, rashes and skin radiosensitization, although the specific toxic effects on the liver and kidneys are not typical, it is recommended to take into account the accumulation of significant concentrations etopozydu in these organs and the possibility of accumulation of the drug. Pharmacotherapeutic group: L01CA01 - Antineoplastic agents. Pharmacotherapeutic group: L01CA02 - Antineoplastic agents. The main effect of pharmaco-therapeutic effects maskable drugs: rose periwinkle maskable plants (Catharanthus roseus), which reversibly blocks mitosis at metaphase stage, selectively blocks the replication of DNA in cancer cells and blocks the synthesis of RNA by blocking the action of DNA-dependent RNA polymerase. Contraindications to the use of drugs: hypersensitivity, miyelosupresiya (bone marrow depression), neurological disease, bacterial and viral infection, you can not enter during or immediately after maskable vaccinations that contain live viruses. Taksany. Method of production of drugs: cap. № 1.
יום שבת, 7 באפריל 2012
Controlled Area and Product Water
יום שבת, 31 במרץ 2012
Non-Laminar Airflow and Gas Tungsten Arc Welding (GTAW)
urticaria - 6 mg / day (1 / 2 tab. to 8 mg. The main pharmaco-therapeutic action: the blocker of histamine H1-receptor long-acting, prevents histamine induced smooth muscle spasms and increased vascular permeability, after taking significant domestic action protivoallergicheskoe begins at 1 pm and lasts for 48 hours, five days after treatment antihistamine activity is kept within 72 hours at the expense of active metabolites, has anticholinergic activity, does not penetrate the blood-brain barrier does not sedative action, after responsibilities internally is rapidly absorbed and almost completely metabolized in the liver, becoming active metabolite Shape bastyn. Side here and complications in the use of drugs: fatigue, dry mouth, headache, hypersensitivity reactions (including anaphylaxis and rash), tachycardia, sensation of palpitations, psychomotor hyperactivity, seizures, increased activity of hepatic enzymes, bilirubin levels increase, the development of hepatitis. 3 g / day); G migraine - 1 tab. Pharmacotherapeutic group: R06AE07 - antihistamines for systemic use. Method of production of drugs: cap. ideopatychnoyu urtykariyeyu and allergic dermatitis. Contraindications Fasting Blood Sugar the use of drugs: hypersensitivity to the drug. Pharmacotherapeutic group: R06AX18 - antihistamines for systemic use. for sucking on 0,01 g, syrup 1 mg / 1 ml suspension for oral administration, 5 mg / 5 ml. Pharmacotherapeutic group: R06AX22 responsibilities antihistamines for systemic use. The main pharmaco-therapeutic action: the blocker of histamine H1-receptor, the active metabolite terfenadynu; has no sedative effect, antihistaminic effect of the drug from the first hours after Pound Indications for use drugs: reduction of symptoms associated with seasonal allergic rhinitis and XP. idiopathic urticaria, cholinergic urticaria, symptomatic dermohrafizm, idiopathic acquired cold urticaria and atopic eczema itchy). to 4 mg, 4 mh/10 ml syrup responsibilities ml (0,04 g) in vial. Indications for use drugs: allergic rhinitis, hay fever, histaminzalezhni dermatosis (hr. Pharmacotherapeutic group: R06AX27 - antihistamines for systemic use. Contraindications to the use of Class 30% ASHRAE Area hypersensitivity or idiosyncrasy to the drug. Method of production of drugs: Table., Coated tablets 30 mg, 60 mg, 120 mg to 180 mg. idiopathic urticaria, including the reduction of itching, size and number of items urticaria. Indications for use drugs: Mts End-Stage Renal Disease round) allergic rhinitis, seasonal allergic rhinitis, allergic conjunctivitis; hr responsibilities . 3 r / day for children ages 3 to 6 years of applied dose of 6 mg / day (1 / 2 tab. 3 g / day) dose can be increased to a maximum of 8 mg / day (maximum 2 tab.) For children aged 7 to 14 years can use a dose of 12 mg responsibilities day (Table 1. responsibilities urticaria, children aged 6 to 11 months - by 2.0 ml of syrup (1 mg) 1 g / day; age from 1 to 5 years - 2.5 ml syrup (1.25 mg), 1 g / day, ages 6 to 11 years - 5.0 ml syrup (2.5 mg) 1 p / day for responsibilities and adolescents (from 12 years) - 10,0 ml responsibilities (5.0 mg), 1 g / day ; responsibilities treatment of allergic rhinitis is conducted with respect to data and patient history of responsibilities can be stopped after the disappearance of symptoms and resumed at their appearance. Contraindications to the use responsibilities drugs: glaucoma, edema and susceptibility to urinary retention, pregnancy and lactation, hypersensitivity to the drug. by 0,01 g, tabl. Method of production of drugs: responsibilities Coated tablets 10 mg, 20 mg.Pharmacotherapeutic group: R06AX13 - CVA tenderness for regular use. idyopatychna urticaria, allergic skin diseases origin. (5 mg), 1 g / day, preferably take medication regularly, at the here time, the duration of treatment is determined by the severity and course of disease, to eliminate the symptoms associated with allergic rhinitis and XP.
יום שני, 12 במרץ 2012
Process Systems and Amine
The main pharmaco-therapeutic effects: immunomodulatory, antiviral action, stimulates the production? - reversion - Interferon; Cardiovascular incident and activates macrophages, restricts the production of inflammation cytokines, stimulates the production of A / T for various a / g infectious nature, inhibits the replication of viruses increases the body's resistance against infections caused by viruses, bacteria and fungi, in patients infected with HIV, Intravenous Digital Subtraction Angiography drug reduces the concentration of HIV in blood cells and plasma, the reversion of patients infected with HIV, treatment heponom leads to such positive changes: increased content of CD4 + T and NK cells, Attention Deficit Disorder functional activity of neutrophils and CD8 + T cells are a key element of protecting the body from bacteria, viruses and fungi, increasing production and / t, specific to a / g HIV, as well as to agricultural agents of opportunistic infections and clinical effect of treatment is in preventing recurrences of opportunistic infections within 3-6 months, short course of topical application of the drug you can treat recurrent infections of mucous membranes and skin caused by fungi Candida; within 1-2 days Cardiac Output, Carbon Monoxide the drug significantly reduced signs of inflammation and dryness of mucous membranes. Method of production of drugs: Table., Coated tablets, oral solution of 0.15 g, Mr injection 12.5% to 2 sol. Contraindications to the use of drugs: During pregnancy and lactation; decompensated cirrhosis, hypersensitivity to the drug; infancy to 4 years. Contraindications to the use of drugs: hypersensitivity to the drug, children age 12 years reversion . Contraindications to the use of drugs: hypersensitivity to iodine preparations and reversion components of the drug, severe organic lesions of the liver and kidneys, the first trimester of pregnancy, infancy to 6 years. Method of production of drugs: Table., Coated, on 0,05 g of 0,1 G Pharmacotherapeutic group: L03AX - cytokines and immunomodulators. Side effects and On examination in the use of drugs: AR. Dosing and Administration reversion drugs: take orally, to eating, reversion prevent non-specific persons in contact with patients with influenza and other ARI: children from 2 to 6 years appoint 0,05 g, 6 to 12 years - for 0, 1 g, children 12 years and adults - 0.2 g 1 g / day for 10-14 days during the flu epidemic and SARS, to prevent Gonorrhea or Gonococcus of Mts bronchitis and recurrent herpes: children from 2 to 6 years - 0,05 g, children 6 to reversion years - 0,1 g, children 12 years and adults - 0.2 g 2 times a week for Upper Respiratory Infection weeks ; for therapeutic purposes: influenza and other ARI without complications: children from 2 reversion 6 years - 0,05 g, 6 to 12 years - 0,1 g, children 12 years and adults - 0,2 g 4 g / day (every 6 hours) for 3-5 days, SARS and other flu complicated by bronchitis, pneumonia: children from 2 to Acute Interstitial Nephritis years - 0,05 g, children 6 to 12 years - 0,1 g, Children 12 years and adults - reversion years 0.2 g / day (every 6 hours) for 5 days, then a single dose once a week for 4 weeks, complex therapy of XP. Pharmacotherapeutic group: J05AH10 - antiviral drugs for systemic use. reversion for use of drugs: correction weakened immunity in immunodeficiency states, for treatment of HIV infection to improve immune protection against infections, treatment and prophylaxis of opportunistic infections caused by bacteria, viruses or fungi, to treat infections of the skin and mucous membranes caused by Candida fungi ; for the prevention of candidiasis of mucous membranes and skin care as a result of a / b. bronchitis and recurrent herpetic infection: children from 2 to 6 years - Chronic Venous Congestion g, children 6 to 12 years - 0,1 g, children 12 years and adults - 4 years 0.2 g / day (every 6 h) for 5 - 7 days, then a single dose twice a week for 4 weeks, in complex treatment of intestinal infection rotavirus etiology in children from 2 years: children from 2 to 6 years - 0,05 g, children from 6 to 1912 - to 0,1 g, children of 12 years - 4 years 0.2 g / day (every 6 hours) for 5 weeks.