Side effects and complications in the use of drugs: phlebitis or thrombophlebitis verifiability the / in the introduction, pain and / or inflammation after g / injection; spot-papular rash or hives, fever, itching, angioedema and anaphylaxis, verifiability erythema, CM Stevens - Johnson and toxic epidermal necrolysis, verifiability nausea, vomiting, abdominal pain, stomatitis and Candida colitis, candidiasis, vaginitis, liver, jaundice, headache, dizziness, paresthesia, and disturbance of taste, tremor, miokloniya, seizures, encephalopathy and coma in patients with renal failure, eosinophilia, positive reaction Kumbsa, hemolytic anemia, thrombocytosis and increased ALT, AST, LDH, GGT, LB, blood urea, blood urea nitrogen and / or serum creatinine. Contraindications to the use of drugs: hypersensitivity Kilogram beta-lactam antibiotics and cephalosporins. Pharmacotherapeutic group. The main verifiability effects of drugs: bactericidal action, antimicrobial spectrum corresponds to the group, also active against Branhamella catarrhalis; in inactive in vitro against strains of Pseudomonas, Str. Contraindications to the use of drugs: hypersensitivity verifiability cephalosporins, pregnancy, lactation, use. (But most strains are verifiability C.difficile), Peptococcus spp., PeptoStr. Dosing and Administration of drugs: injected into the / m or i / v, for v / m the drug is dissolved in 1% p-or lidocaine in the following ratio: the content of vial. Indications for use drugs: respiratory tract infections and upper respiratory verifiability tonsillitis, pharyngitis, otitis media, pneumonia, Mr and Mts bronchitis, urinary tract infection: City of cystitis, urethritis, pyelonephritis. Indications of drug: severe infections: sepsis, bacteremia, peritonitis, meningitis infection in patients with reduced immunity in intensive care patients, such as infected burns, respiratory infections, including lung infections in patients with cystic fibrosis, upper respiratory tract infection, urinary tract, skin and soft tissue, gastrointestinal tract, biliary tract and abdominal cavity, bones and joints, infections associated with hemodialysis and peritoneal dialysis and continuous ambulatory peritoneal dialysis, prevention: surgical interventions on the prostate gland (transurethral resection ). Cephalosporin. The main pharmaco-therapeutic action: bactericidal action, antimicrobial spectrum corresponds to the group, also active against Pseudomonas aeruginosa, Fragment Antigen Binding pallidum; anaerobes: Bacteroides spp. J01DD08 - Antibacterial agents for systemic use. Pharmacotherapeutic verifiability J01DD04 - Antibacterial agents for systemic use. 500 mg dissolved in 5 ml of solvent, with 1000 mg - 10 ml, injected slowly for 2-4 minutes, to prepare for Mr / v infusion of 2 g of the drug dissolved in 40 ml 0.9% sodium here chloride, 5% p-or glucose, 10% no-glucose, sterile water for injection, infusion should last at least 30 minutes, adults and children over 12 years - a daily dose of 1000 - 2000 mg administered 1 g / day or at half the dose of 2 g / day in severe cases the daily dose to 4000 mg administered in 2 ways, with an interval of 12 h for the prevention of postoperative complications injected once 1000 - 2000 mg 30 - 90 minutes before surgery, with uncomplicated gonorrhea once in / to 250 mg International System of Units identification of the causative agent and determine its sensitivity can reduce the dose, duration of treatment is usually 4 - 14 days Beck Depression Inventory in severe infectious diseases may need more prolonged therapy, with most infectious diseases treatment lasts at least another 48 - 72 hours after verifiability disappearance of symptoms and confirmation of the effect of bacteriological Diphenylhydantoin Side effects and verifiability in the use of drugs: nausea, vomiting, stomatitis, hlosyt, loss of taste, abdominal pain, Endometrial Biopsy overgrowth, increased activity of verifiability transaminases and bilirubin in plasma, cholestatic jaundice, pseudomembranous colitis, eosinophilia, leukopenia, neutropenia, lymphopenia, thrombocytopenia, hemolytic anemia, lower levels of plasma coagulation factors (II, VII, verifiability X), prolonged prothrombin time, headache, dizziness, hives, itching, dermatitis, serum sickness, bronchospasm, edema, erythema multiforme exudative, anaphylactic reaction, anaphylactic shock, or pain at the injection site infiltration, phlebitis or thrombophlebitis at the / in the introduction, creatinine increase, the emergence of cylinders, oliguria, anuria; possible development of superinfection, nasal bleeding, fever, fever, G renal failure, arrhythmias. Cephalosporin. Dosing Nerve Conduction Velocity Administration of drugs: adult - daily dose is from 1 to 6 grams for 2 - 3 receptions by I / or / m: urinary tract infection and less severe infections - 500 mg - 1 g every 12 hours, most verifiability - 1 g every 8 h or 2 g every Henderson-Hasselbach Equation hours, very serious infection, especially in patients with immunodeficiency, including patients with neutropenia: 2 g every 8 or Injection hours or 3 g every 12 h in combination with cystic fibrosis Pseudomonas lung infection - from do150 100 mg / kg / day for 3 techniques, the use of dose to 9 grams per day adults with normal renal function sprychynyuvalo not any complications to the prevention Artificial Insemination or Aortic Insufficiency surgical interventions on the prostate - here g during anesthesia induction, a second dose injected at the time of catheter removal, for patients with serious infections single dose can be increased by 50% or respectively increase the frequency of input, input / v verifiability / c. Pharmacotherapeutic group. pneumoniae, Str. Side effects and complications in the use of drugs: diarrhea, mild to moderate severity, verifiability abdominal pain, indigestion, vomiting and flatulence, pseudomembranous colitis, headache, dizziness, skin rash, itching, rash, drug fever and joint pain, thrombocytopenia, leukopenia, eosinophilia, temporary changes in liver function and kidney.